Structure of PDB 7lo6 Chain A

Receptor sequence
>7lo6A (length=363) Species: 11676 (Human immunodeficiency virus 1) [Search protein sequence]
NLWVTVYYGVPVWKDAETTLFCASDAKAYETEKHNVWATHACVPTDPNPQ
EIHLENVTEEFNMWKNNMVEQMHTDIISLWDQSLKPCVKLTPLCNCNTSA
ITQACPKVSFEPIPIHYCAPAGFAILKCKDKKFNGTGPCPSVSTVQCTHG
IKPVVSTQLLLNGSLAEEEVMIRSENITNNAKNILVQFNTPVQINCTRPN
DIRQAHCNVSKATWNETLGKVVKQLRKHFGNNTIIRFANSSGGDLEVTTH
SFNCGGEFFYCNTSGLFNSTWISNDSITLPCRIKQIINMWQRIGQAMYAP
PIQGVIRCVSNITGLILTRDGGSTTETFRPGGGDMRDNWRSELYKYKVVK
IEPLGVAPTRCKR
3D structure
PDB7lo6 Cryo-EM structures of HIV-1 trimer bound to CD4-mimetics BNM-III-170 and M48U1 adopt a CD4-bound open conformation.
ChainA
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5VG A F376 N425 M426 W427 R429 I430 G472 G473 F252 N288 M289 W290 R292 I293 G332 G333
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:7lo6, PDBe:7lo6, PDBj:7lo6
PDBsum7lo6
PubMed33782388
UniProtQ2N0S6

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