Structure of PDB 7lo1 Chain A

Receptor sequence
>7lo1A (length=422) Species: 227321 (Aspergillus nidulans FGSC A4) [Search protein sequence]
PLSIAIIGGGIIGLMTALGLLHRNIGKVTIYERASAWPDIGAAFAFTGIA
RECMQRLDPAILSALSKVAQRNPHDKVRYWDGFHPKSKEEAQDPEKSVLF
EIEEKNMAYWACLRGVFHAEMARLLPERVVRFGKRLVAYEDGGDQKVVLR
FEDGEVEEADIVIACDGVHSTARRVLLGAEHPAANARYSRKAVYRALVPM
PAAIDALGTEKAHVQIAHCGPDAHIVSFPVNNAQIYNVFLFTHDSNEWTH
GHTMTVPSSKEEILSAVENWGPHIKELASLFPEQLSKYAIFDQADHPLPY
YAAGRVALAGDAAHASSPFHGAGACMGVEDALVLAELLEKVQNKKSNIEL
ALKTYSDVRIERSQWLVKSSREMGDLYEWRYEDIGGDGVKCKAEWERRSR
VIWDFDVQGMVDQAREAYERAV
3D structure
PDB7lo1 Deciphering the evolution of flavin-dependent monooxygenase stereoselectivity using ancestral sequence reconstruction.
ChainA
Resolution2.09 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.-.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD A G17 G19 I20 I21 E41 R42 I49 A51 A52 F53 R123 R144 L145 C174 D175 G176 T180 Y297 D320 A331 G8 G10 I11 I12 E32 R33 I40 A42 A43 F44 R114 R135 L136 C165 D166 G167 T171 Y288 D311 A322
Gene Ontology
Molecular Function
GO:0004497 monooxygenase activity
GO:0071949 FAD binding
Biological Process
GO:0044550 secondary metabolite biosynthetic process
GO:1900554 asperfuranone biosynthetic process
Cellular Component
GO:0005575 cellular_component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7lo1, PDBe:7lo1, PDBj:7lo1
PDBsum7lo1
PubMed37014851
UniProtQ5BEJ7|AFOD_EMENI FAD-dependent monooxygenase afoD (Gene Name=afoD)

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