Structure of PDB 7lnx Chain A

Receptor sequence
>7lnxA (length=234) Species: 1291540 (Methanomethylophilus alvi) [Search protein sequence]
MILIKLGGSVITDKSEYHKFNKETVSRLADEIRRSGQDVMVVHGAGSFGH
VIAKKYAIQDGHVDDGQIPAAARIMCDTRELSSMVVEELLAQGIPAVSVA
PGSCFVMEDGKLIVDNEEPIRRLADLGIMPVMFGDVVPDRKKGFAAVSGD
QCMEVLCRMFDPEKVVFVSDIDGLYTADPKTDKKARLIGEVTREAMLRMT
DRNRRCYLVNGNAPNRLYSLLKGETVTCTVAKGG
3D structure
PDB7lnx Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus .
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.4.26: isopentenyl phosphate kinase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP A K5 S9 I171 L174 Y175 A177 D178 P179 K180 K5 S9 I171 L174 Y175 A177 D178 P179 K180
BS02 Y7D A G8 K14 G44 A45 G46 G49 H50 G134 D135 A146 S148 G149 G8 K14 G44 A45 G46 G49 H50 G134 D135 A146 S148 G149
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0102043 isopentenyl phosphate kinase activity
Biological Process
GO:0008299 isoprenoid biosynthetic process
GO:0016310 phosphorylation
Cellular Component
GO:0005829 cytosol

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7lnx, PDBe:7lnx, PDBj:7lnx
PDBsum7lnx
PubMed34905349
UniProtM9SEQ1

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