Structure of PDB 7ll6 Chain A

Receptor sequence
>7ll6A (length=286) Species: 470137 (Brucella suis ATCC 23445) [Search protein sequence]
PVYSLTGKKIFVAGHTGMVGSAILRRLQHEDCDIITAAHSVLDLTRQGPT
ENFISGHRPDVIIIAAARVGGILANSRFPADFLYDNLAIGMNLIHAAHQI
GVERLLWLGSSCIYPRDAAQPLTEDALLTGPLEPTNEAYAIAKIAGLKYA
QSCARQFGDRFITAMPTNLYGPNDNFDPTSSHVLPALIRRVHEARMRGAE
PLREFLHVDDLADACLHLLRFYNGIEPVNIGSGEEISIKELALTVARIVG
YERKLLDTSRIEALGWQPRIRLEDGLRDVYRNWLEE
3D structure
PDB7ll6 Crystal structure of fucose synthetase family protein from Brucella suis ATCC 23445
ChainA
Resolution2.25 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) S121 S122 C123 Y150 K154 H193
Catalytic site (residue number reindexed from 1) S110 S111 C112 Y139 K143 H182
Enzyme Commision number 1.1.1.271: GDP-L-fucose synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP A G25 T27 G28 M29 V30 H50 L55 A77 A78 V80 L119 G120 S121 S122 Y150 K154 P177 T178 L180 G14 T16 G17 M18 V19 H39 L44 A66 A67 V69 L108 G109 S110 S111 Y139 K143 P166 T167 L169
BS02 MG A G28 V30 G31 G17 V19 G20
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0016853 isomerase activity
GO:0050577 GDP-L-fucose synthase activity
GO:0070401 NADP+ binding
Biological Process
GO:0009226 nucleotide-sugar biosynthetic process
GO:0042351 'de novo' GDP-L-fucose biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7ll6, PDBe:7ll6, PDBj:7ll6
PDBsum7ll6
PubMed
UniProtA9WYA5

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