Structure of PDB 7lel Chain A

Receptor sequence
>7lelA (length=114) Species: 9606 (Homo sapiens) [Search protein sequence]
STVKVTEQLRHCSEILKEMLAKKHFSYAWPFYNPVDVNALGLHNYYDVVK
NPMDLGTIKEKMDNQEYKDAYKFAADVRLMFMNCYKYNPPDHEVVTMARM
LQDVFETHFSKIPI
3D structure
PDB7lel Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors.
ChainA
Resolution2.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BMF A W293 F295 P298 V299 D300 L304 N352 H356 V358 W29 F31 P34 V35 D36 L40 N88 H92 V94 BindingDB: Kd=172nM
External links
PDB RCSB:7lel, PDBe:7lel, PDBj:7lel
PDBsum7lel
PubMed34710325
UniProtQ58F21|BRDT_HUMAN Bromodomain testis-specific protein (Gene Name=BRDT)

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