Structure of PDB 7lde Chain A

Receptor sequence
>7ldeA (length=776) Species: 10090 (Mus musculus) [Search protein sequence]
ANFPNNIQIGGLFPNQQSQEHAAFRFALSQLTEPPKLLPQIDIVNISDSF
EMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTS
NQFVLQLRPELQEALISIIDHYKWQTFVYIYDADRGLSVLQRVLDTAAEK
NWQVTAVNILTTTEEGYRMLFQDLEKKKERLVVVDCESERLNAILGQIVK
LEKNGIGYHYILANLGFMDIDLNKFKESGANVTGFQLVNYTDTIPARIMQ
QWRTSDARDHTRVDWKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRG
NAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRTNYTLHV
IEMKHDGIRKIGYWNEDDKFVPATYIVTTILEDPYVMLKKNANQFEGNDR
YEGYCVELAAEIAKHVGYSYRLEIVSDGKYGARDPDTKAWNGMVGELVYG
RADVAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDP
LAYEIWMCIVFAYIGVSVVLFLVSRFSNEFGIFNSLWFSLGAFMQQGCDI
SPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAK
QTEIAYGTLEAGSTKEFFRRSKIAVFEKMWTYMKSAEPSVFVRTTEEGMI
RVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSA
LRGPVNLAVLKLSEQGVLDKLKSKWWYDKGECGSKDSGSKDKTSALSLSN
VAGVFYILIGGLGLAMLVALIEFCYK
3D structure
PDB7lde Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition.
ChainA
Resolution3.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZK1 A D399 Y446 T476 R481 E701 D383 Y430 T460 R465 E664
BS02 XVD A M523 C524 F527 M507 C508 F511
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0015276 ligand-gated monoatomic ion channel activity
GO:0038023 signaling receptor activity
Biological Process
GO:0006811 monoatomic ion transport
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7lde, PDBe:7lde, PDBj:7lde
PDBsum7lde
PubMed33981040
UniProtP23818|GRIA1_MOUSE Glutamate receptor 1 (Gene Name=Gria1)

[Back to BioLiP]