Structure of PDB 7lcc Chain A

Receptor sequence

>7lccA (length=1369) Species: 32630 (synthetic construct)

EDAILEHSCGGMTVRCEFCLSLNFSDEKPSDGKFTRCCSKGKVCPNDIHF
PDYPAYLKRLMTNEDSDSKNFMENIRSINSSFAFASMGANIASPSGYGPY
CFRIHGQVYHRTGTLHPSDGVSRKFAQLYILDTAEATSKRLAMPENQGCS
ERLMININNLMHEINELTKSYKMLHEVEKEAQSEAAAKGIAPTEVTMAIK
YDRNSDPGRYNSPRVTEVAVIFRNEDGEPPFERDLLIHCKPDPNNPNATK
MKQISILFPTLDAMTYPILFPHGEKGWGTDIALRRVTQMQYYGFHLSVRD
TFNPILNAGKLTQQFIVDSYSKMEANRINFIKANQSKLRVEKYSGLMDYL
KSRSENDNVPIGKMIILPSSFEGSPRNMQQRYQDAMAIVTKYGKPDLFIT
MTCNPKWADITNNLQRWQKVENRPDLVARVFNIKLNALLNDICKFHLFGK
VIAKIHVIEFQKRGLPHAHILLILDSESKLRSEDDIDRIVKAEIPDEDQC
PRLFQIVKSNMVHGPCGIQNPNSPCMENGKCSKGYPKEFQNATIGNIDGY
PKYKRRSGSTMSIGNKVVDNTWIVPYNPYLCLKYNCHINVEVCASIKSVK
YLFKYIYKGHDCANIQISEKNIINHDEVQDFIDSRYVSAPEAVWRLFAMR
MHDQSHAITRLAIHLPNDQNLYFHTDDFAEVLDRAKRHNSTLMAWFLLNR
EDSDARNYYYWEIPQHYVFNNSLWTKRRKGGNKVLGRLFTVSFREPERYY
LRLLLLHVKGAISFEDLRTVGGVTYDTFHEAAKHRGLLLDDTIWKDTIDD
AIILNMPKQLRQLFAYICVFGCPSAADKLWDENKSHFIEDFCWKLHRREG
ACVNCEMHALNEIQEVFTLHGMKCSHFKLPDYPLLMNANTCDQLYEQQQA
EVLINSLNDEQLAAFQTITSAIEDQTVHPKCFFLDGPGGSGQTYLYKVLT
HYIRGRGGTVLPTASTGIAANLLLGGRTFHSQYKLPIPLNETSISRLDIK
SEVAKTIKKAQLLIIDECTMASSHAINAIDRLLREIMNLNVAFGGKVLLL
GGDFRQCLSIVPHAMRSAIVQTSLKYCNVWGCFRKLSLKTNMRSEDSAYS
EWLVKLGDGKLDSSFHLGMDIIEIPHEMICNGSIIEATFGNSISIDNIKN
ISKRAILCPKNEHVQKLNEEILDILDGDFHTYLSDDSIDSTDDAEKENFP
IEFLNSITPSGMPCHKLKLKVGAIIMLLRNLNSKWGLCNGTRFIIKRLRP
NIIEAEVLTGSAEGEVVLIPRIDLSPSDTGLPFKLIRRQFPVMPAFAMTI
NKSQGQTLDRVGIFLPEPVFAHGQLYVAFSRVRRACDVKVKVVNTSSQGK
LVKHSESVFTLNVVYREIL

3D structure

• PDB: 7lcc The large bat Helitron DNA transposase forms a compact monomeric assembly that buries and protects its covalently bound 5'-transposon end.
• Chain: A
• Resolution: 3.66 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	dna	A	Q461 L493 P494 R502 Y727 F865 T866 S868 R870 T1104 I1113 R1122 I1186 K1286 N1287 S1336 R1355 N1356 N1365 S1403 K1428	Q335 L367 P368 R376 Y601 F739 T740 S742 R744 T978 I987 R996 I1060 K1160 N1161 S1210 R1229 N1230 N1239 S1277 K1302
BS02	ZN	A	C125 C128 C146 C147	C16 C19 C37 C38

Gene Ontology

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UnboundLocalError

Python 3.6.8: /usr/bin/python3 Sun Feb 16 22:31:38 2025

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1443                 pubmed=display_regular_ligand(pdbid,asym_id,lig3,ligIdx,title)

   1444         else:

=> 1445             pubmed,uniprot=display_protein_receptor(pdbid,asym_id,title)

   1446     

   1447     uniprot_line=''

pubmed = '', uniprot = '', display_protein_receptor = <function display_protein_receptor>, pdbid = '7lcc', asym_id = 'A', title = "The large bat Helitron DNA transposase forms a c...protects its covalently bound 5'-transposon end. "

 /var/www/html/BioLiP/pdb.cgi in display_protein_receptor(pdbid='7lcc', asym_id='A', title="The large bat Helitron DNA transposase forms a c...protects its covalently bound 5'-transposon end. ")

    839 

    840     if go:

=>  841         display_go(go,uniprot,pdbid,asym_id)

    842     return pubmed,uniprot

    843 

global display_go = <function display_go>, go = '0000723,0003678,0006281', uniprot = '', pdbid = '7lcc', asym_id = 'A'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0000723,0003678,0006281', uniprot='', pdbid='7lcc', asym_id='A')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>