Structure of PDB 7lc7 Chain A

Receptor sequence
>7lc7A (length=178) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]
GTVLIHVCCAPDLLTTIFHVRDAEFFFYNPNIQPLSEYEKRREAVDKVAN
HFSLNVRYGEYSTEEIRKWYTAVKDYKLGEGSKRCERCISFLLERTAQEA
RKRGHESFSTTLLASPRKNLPMIENIGKTIEEKYGVKFFFKNFRKGGAYQ
EGVRLSKELGIYRQNYCGCVFSLLERRE
3D structure
PDB7lc7 The epoxyqueuosine reductase QueH in the biosynthesis of tRNA queuosine is a unique metalloenzyme
ChainA
Resolution1.58 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.17.99.6: epoxyqueuosine reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 A R86 C87 C90 C169 C171 R84 C85 C88 C167 C169
BS02 5GP A P12 D13 S117 K120 R165 Q166 N167 Y168 C169 P11 D12 S115 K118 R163 Q164 N165 Y166 C167
BS03 FE A C9 C10 D13 C8 C9 D12
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0052693 epoxyqueuosine reductase activity
Biological Process
GO:0006400 tRNA modification
GO:0008033 tRNA processing
GO:0008616 queuosine biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7lc7, PDBe:7lc7, PDBj:7lc7
PDBsum7lc7
PubMed
UniProtQ9WZJ0|QUEH_THEMA Epoxyqueuosine reductase QueH (Gene Name=queH)

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