Structure of PDB 7lc5 Chain A

Receptor sequence
>7lc5A (length=178) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]
TVLIHVCCAPDLLTTIFHVRDAEFFFYNPNIQPLSEYEKRREAVDKVANH
FSLNVRYGEYSTEEIRKWYTAVKDYKDLGEGSKRCERCISFLLERTAQEA
RKRGHESFSTTLLASPRKNLPMIENIGKTIEEKYGVKFFFKNFRKGGAYQ
EGVRLSKELGIYRQNYCGCVFSLLERRE
3D structure
PDB7lc5 Epoxyqueuosine Reductase QueH in the Biosynthetic Pathway to tRNA Queuosine Is a Unique Metalloenzyme.
ChainA
Resolution1.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.17.99.6: epoxyqueuosine reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 A N32 E82 R86 C87 C90 C169 C171 N30 E80 R84 C85 C88 C167 C169
BS02 FE A C9 C10 D13 C7 C8 D11
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
GO:0052693 epoxyqueuosine reductase activity
Biological Process
GO:0006400 tRNA modification
GO:0008033 tRNA processing
GO:0008616 queuosine biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7lc5, PDBe:7lc5, PDBj:7lc5
PDBsum7lc5
PubMed34652139
UniProtQ9WZJ0|QUEH_THEMA Epoxyqueuosine reductase QueH (Gene Name=queH)

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