Structure of PDB 7lak Chain A

Receptor sequence
>7lakA (length=120) Species: 9606 (Homo sapiens) [Search protein sequence]
GRVTNQLQYLHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMD
MGTIKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKI
FLQKVASMPQEEQELVVTIP
3D structure
PDB7lak Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors.
ChainA
Resolution1.831 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 IBI A W97 P98 Q101 V103 Y155 N156 I162 W25 P26 Q29 V31 Y83 N84 I90
External links
PDB RCSB:7lak, PDBe:7lak, PDBj:7lak
PDBsum7lak
PubMed34710325
UniProtP25440|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)

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