Structure of PDB 7l9l Chain A

Receptor sequence
>7l9lA (length=113) Species: 9606 (Homo sapiens) [Search protein sequence]
SMGKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIK
HPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARK
LQDVFEMRFAKMP
3D structure
PDB7l9l Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors.
ChainA
Resolution1.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 R78 A W332 P333 V338 L343 L345 Y390 N391 H395 W29 P30 V35 L40 L42 Y87 N88 H92
External links
PDB RCSB:7l9l, PDBe:7l9l, PDBj:7l9l
PDBsum7l9l
PubMed34710325
UniProtQ15059|BRD3_HUMAN Bromodomain-containing protein 3 (Gene Name=BRD3)

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