Structure of PDB 7l97 Chain A

Receptor sequence
>7l97A (length=175) Species: 9606 (Homo sapiens) [Search protein sequence]
GVEGLRCVVLPEDLCHKFLQLAESNTVRGIETCGILCGKLTHNEFTITHV
IVPKQSAGPDYCDMENVEELFNVQDQHDLLTLGWIHTHPTQTAFLSSVDL
HTHCSYQLMLPEAIAIVCSPKHKDTGIFRLTNAGMLEVSACKKKGFHPHT
KEPRLFSICKHVLVKDIKIIVLDLR
3D structure
PDB7l97 Structural and functional characterization of ubiquitin variant inhibitors for the JAMM-family deubiquitinases STAMBP and STAMBPL1.
ChainA
Resolution2.01 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.19.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H362 C402 H408 H410 H101 C141 H147 H149
BS02 ZN A H347 H349 D360 H86 H88 D99
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
GO:0008237 metallopeptidase activity
GO:0061578 K63-linked deubiquitinase activity
GO:0140492 metal-dependent deubiquitinase activity
Biological Process
GO:0016579 protein deubiquitination
GO:0070536 protein K63-linked deubiquitination

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Molecular Function
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Biological Process
External links
PDB RCSB:7l97, PDBe:7l97, PDBj:7l97
PDBsum7l97
PubMed34425109
UniProtQ96FJ0|STALP_HUMAN AMSH-like protease (Gene Name=STAMBPL1)

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