Structure of PDB 7l5f Chain A

Receptor sequence
>7l5fA (length=250) Species: 1423 (Bacillus subtilis) [Search protein sequence]
MTVKKLYFIPAGRCMLDHSSVNSALTPGKLLNLPVWCYLLETEEGPILVD
TGMPESAVNNEGLFNGTFVEGQILPKMTEEDRIVNILKRVGYEPDDLLYI
ISSHLHFDHAGGNGAFTNTPIIVQRTEYEAALHREEYMKECILPHLNYKI
IEGDYEVVPGVQLLYTPGHSPGHQSLFIETEQSGSVLLTIDASYTKENFE
DEVPFAGFDPELALSSIKRLKEVVKKEKPIIFFGHDIEQEKSCRVFPEYI
3D structure
PDB7l5f Cyclobutanone Inhibitor of Cobalt-Functionalized Metallo-gamma-Lactonase AiiA with Cyclobutanone Ring Opening in the Active Site.
ChainA
Resolution1.51 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.1.81: quorum-quenching N-acyl-homoserine lactonase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CO A D108 H109 D191 H235 D108 H109 D191 H235
BS02 CO A H104 H106 H169 D191 H104 H106 H169 D191
BS03 XNG A H106 F107 D108 H109 E136 H169 D191 Y194 H235 H106 F107 D108 H109 E136 H169 D191 Y194 H235
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0102007 acyl-L-homoserine-lactone lactonohydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:7l5f, PDBe:7l5f, PDBj:7l5f
PDBsum7l5f
PubMed34095651
UniProtP0CJ63|AHLLA_BACTK N-acyl homoserine lactonase AiiA (Gene Name=aiiA)

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