Structure of PDB 7l4f Chain A

Receptor sequence

>7l4fA (length=350) Species: 3702 (Arabidopsis thaliana) [Search protein sequence]

PIRLPNPMIGFGVPNEPGLITHRSLPELARGPPFFYYENVALTPKGVWET
ISRHLFEIPPEFVDSKYFCVAARKRGYIHNLPINNRFQIQPPPKYTIHDA
FPLSKRWWPEWDKRTKLNCILTCTGSAQLTNRIRVALEPYNEEPEPPKHV
QRYVIDQCKKWNLVWVGKNKAAPLEPDEMESILGFPKNHTRGGGMSRTER
FKSLGNSFQVDTVAYHLSVLKPIFPHGINVLSLFTGIGGGEVALHRLQIK
MKLVVSVEISKVNRNILKDFWEQTNQTGELIEFSDIQHLTNDTIEGLMEK
YGGFDLVIGGSPCNNLAGGNRVSRVGLEGDQSSLFFEYCRILEVVRARMR

3D structure

PDB

7l4f Substrate deformation regulates DRM2-mediated DNA methylation in plants.

Chain

Resolution

2.55 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

2.1.1.37: DNA (cytosine-5-)-methyltransferase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	S400 Q402 W435 S470 R471 T472 G592 R595	S126 Q128 W161 S196 R197 T198 G318 R321
BS02	dna	A	E312 V314 R347 R349 N392 T396 C397 N480 C587 N588 G592 R595 V596	E38 V40 R73 R75 N118 T122 C123 N206 C313 N314 G318 R321 V322
BS03	SAH	A	N480 S481 F482 F508 T509 E532 I533 S558 D559 I560 L608	N206 S207 F208 F234 T235 E258 I259 S284 D285 I286 L334

Gene Ontology

	Molecular Function
GO:0008168	methyltransferase activity

View graph for
Molecular Function

External links

PDB	RCSB:7l4f, PDBe:7l4f, PDBj:7l4f
PDBsum	7l4f
PubMed	34078593
UniProt	Q9M548\|DRM2_ARATH DNA (cytosine-5)-methyltransferase DRM2 (Gene Name=DRM2)

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