Structure of PDB 7l1d Chain A

Receptor sequence
>7l1dA (length=274) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTIQIMYG
CDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAA
HEAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRW
3D structure
PDB7l1d Immunogenicity and therapeutic targeting of a public neoantigen derived from mutated PIK3CA.
ChainA
Resolution3.11 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 E63 N66 D77 Y84 Y99 R114 T143 K146 W147 E152 L156 Y159 W167 Y7 E63 N66 D77 Y84 Y99 R114 T143 K146 W147 E152 L156 Y159 W167
External links
PDB RCSB:7l1d, PDBe:7l1d, PDBj:7l1d
PDBsum7l1d
PubMed35484264
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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