Structure of PDB 7l17 Chain A

Receptor sequence
>7l17A (length=453) Species: 99287 (Salmonella enterica subsp. enterica serovar Typhimurium str. LT2) [Search protein sequence]
SISMTTKLSYGFGAFGKDFAIGIVYMYLMYYYTDVVGLSVGLVGTLFLVA
RIWDAINCPIMGWIVNATRSRWGKFKPWILIGTLTNSLVLFLLFSAHLFE
GTAQVVFVCVTYILWGMTYTIMDIPFWSLVPTITLDKREREQLVPFPRFF
ASLAGFVTAGITLPFVSYVGGADRGFGFQMFTLVLIAFFIASTIVTLRNV
HEVYSSDNGVTAGRPHLTLKTIVGLIYKNDQLSCLLGMALAYNIASNIIN
GFAIYYFTYVIGDADLFPYYLSYAGAANLLTLIVFPRLVKMLSRRILWAG
ASVMPVLSCAGLFAMALADIHNAALIVAAGIFLNIGTALFWVLQVIMVAD
TVDYGEFKLNIRCESIAYSVQTMVVKGGSAFAAFFIALVLGLIGYTPNVA
QSAQTLQGMQFIMIVLPVLFFMMTLVLYFRYYRLNGDMLRKIQIHLLDKY
RKT
3D structure
PDB7l17 X-ray crystallography reveals molecular recognition mechanism for sugar binding in a melibiose transporter MelB.
ChainA
Resolution3.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 9PG A K18 D19 Y26 D124 W128 R149 W342 T373 V376 K17 D18 Y25 D123 W127 R148 W341 T372 V375
Gene Ontology
Molecular Function
GO:0015293 symporter activity
Biological Process
GO:0006814 sodium ion transport
GO:0008643 carbohydrate transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7l17, PDBe:7l17, PDBj:7l17
PDBsum7l17
PubMed34341464
UniProtP30878|MELB_SALTY Melibiose permease (Gene Name=melB)

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