Structure of PDB 7l0a Chain A

Receptor sequence
>7l0aA (length=249) Species: 1280 (Staphylococcus aureus) [Search protein sequence]
GLVPRGSHMAYISLNYHSPTIGMHQNLTVILPEDQSFFNSDTTVKPLKTL
MLLHGLSSDETTYMRYTSIERYANEHKLAVIMPNVDHSAYANMAYGHSYY
DYILEVYDYVHQIFPLSKKRDDNFIAGHSMGGYGTIKFALTQGDKFAKAV
PLSAVFEAQNLMDLEWNDFSKEAEHDPYYLLDKAVAEDKQIPKLLIMCGK
QDFLYQDNLDFIDYLSRINVPYQFEDGPGDHDYAYWDQAIKRAITWMVN
3D structure
PDB7l0a Structure-guided microbial targeting of antistaphylococcal prodrugs.
ChainA
Resolution1.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.2.12: S-formylglutathione hydrolase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG A L47 S120 M121 L56 S129 M130
Gene Ontology
Molecular Function
GO:0016788 hydrolase activity, acting on ester bonds
GO:0018738 S-formylglutathione hydrolase activity
Biological Process
GO:0046294 formaldehyde catabolic process
Cellular Component
GO:0005829 cytosol

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:7l0a, PDBe:7l0a, PDBj:7l0a
PDBsum7l0a
PubMed34279224
UniProtQ2FUY3

[Back to BioLiP]