Structure of PDB 7kzg Chain A

Receptor sequence
>7kzgA (length=144) Species: 9606 (Homo sapiens) [Search protein sequence]
KWTPPRSPFNLVQETLFHDPWKLLIATIFLNRTSGKMAIPVLWKFLEKYP
SAEVARTADWRDVSELLKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELHG
IGKYGNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEKLSLS
3D structure
PDB7kzg Structural Insights into the Mechanism of Base Excision by MBD4.
ChainA
Resolution1.68 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A L466 N467 R468 T469 S470 G471 H535 G536 I537 G538 Y540 D560 L30 N31 R32 T33 S34 G35 H99 G100 I101 G102 Y104 D124
BS02 dna A R468 M473 P505 G507 L508 Y509 D510 L511 R32 M37 P69 G71 L72 Y73 D74 L75
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003824 catalytic activity
Biological Process
GO:0006281 DNA repair
GO:0006284 base-excision repair

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Molecular Function
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Biological Process
External links
PDB RCSB:7kzg, PDBe:7kzg, PDBj:7kzg
PDBsum7kzg
PubMed34107280
UniProtO95243|MBD4_HUMAN Methyl-CpG-binding domain protein 4 (Gene Name=MBD4)

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