Structure of PDB 7kz0 Chain A

Receptor sequence
>7kz0A (length=144) Species: 9606 (Homo sapiens) [Search protein sequence]
KWTPPRSPFNLVQETLFHDPWKLLIATIFLNRTSGKMAIPVLWKFLEKYP
SAEVARTADWRDVSELLKPLGLYDLRAKTIVKFSDEYLTKQWKYPIELHG
IGKYGNDSYRIFCVNEWKQVHPEDHKLNKYHDWLWENHEKLSLS
3D structure
PDB7kz0 Structural Insights into the Mechanism of Base Excision by MBD4.
ChainA
Resolution1.57 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A L447 Q449 L466 N467 R468 T469 S470 G536 G538 Y540 D560 K562 L11 Q13 L30 N31 R32 T33 S34 G100 G102 Y104 D124 K126
BS02 dna A R468 P505 L506 G507 L508 Y509 D510 L511 R32 P69 L70 G71 L72 Y73 D74 L75
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003824 catalytic activity
Biological Process
GO:0006281 DNA repair
GO:0006284 base-excision repair

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Molecular Function
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Biological Process
External links
PDB RCSB:7kz0, PDBe:7kz0, PDBj:7kz0
PDBsum7kz0
PubMed34107280
UniProtO95243|MBD4_HUMAN Methyl-CpG-binding domain protein 4 (Gene Name=MBD4)

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