Structure of PDB 7kxa Chain A

Receptor sequence
>7kxaA (length=268) Species: 1768 (Mycobacterium kansasii) [Search protein sequence]
AGLLEGKRILVSGIITDSSIAFHIARVAQEQGAQLVLTGFDRLRLIQRIT
DRLPEKAPLLELDVQNDEHLATLADRVVEVIGEGNKLDGLVHSIGFMPQS
GMGINPFFDAPYEDVSKGIHISAYSYASMAKALLPIMNRGGSIVGMDFDP
SRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMAA
IVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDPTPVAKTVCALLSEWLP
ATTGDIIFADGGAHTQLL
3D structure
PDB7kxa Crystal structure of Enoyl-[acyl-carrier-protein] reductase [NADH] (InhA) from Mycobacterium kansasii in complex with NAD
ChainA
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.3.1.9: enoyl-[acyl-carrier-protein] reductase (NADH).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD A G14 I16 S20 I21 F41 D64 V65 S94 I95 I122 M147 D148 F149 K165 P193 I194 T196 G13 I15 S19 I20 F40 D63 V64 S93 I94 I121 M146 D147 F148 K164 P192 I193 T195
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004318 enoyl-[acyl-carrier-protein] reductase (NADH) activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006633 fatty acid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7kxa, PDBe:7kxa, PDBj:7kxa
PDBsum7kxa
PubMed
UniProtA0A1V3XDT0

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