Structure of PDB 7ksf Chain A

Receptor sequence
>7ksfA (length=742) Species: 2170195 (Eastern chimpanzee simian foamy virus) [Search protein sequence]
QLLQPLPAEIKGTKLLAHWASGATITCIPESFLEDEQPIKKTLIKTEKQQ
NVYYVTFKVKGRKVEAEVIASPYEYILLSPTDVPWLTQQPLQLTILVPLQ
EYQEKILSKTALPEDQKQQLKTLFVKYDNLWQHWENQVGHRKIRPHNIAT
GDYPPRPQKQYPINPKAKPSIQIVIDDLLKQGVLTPQNSTMNTPVYPVPK
PDGRWRMVLDYREVNKTIPLTAAQNQHSAGILATIVRQKYKTTLDLANGF
WAHPITPESYWLTAFTWQGKQYCWTRLPQGFLNSPALFTADVVDLLKEIP
NVQVYVDDIYLSHDDPKEHVQQLEKVFQILLQAGYVVSLKKSEIGQKTVE
FLGFNITKEGRGLTDTFKTKLLNITPPKDLKQLQSILGLLNFARNFIPNF
AELVQPLYNLIASAKGKYIEWSEENTKQLNMVIEALNTASNLEERLPEQR
LVIKVNTSPSAGYVRYYNETGKKPIMYLNYVFSKAELKFSMLEKLLTTMH
KALIKAMDLAMGQEILVYSPIVSMTKIQKTPLPERKALPIRWITWMTYLE
DPRIQFHYDKTLPELKHIPDVYTSSQSPVKHPSQYEGVFYTDGSAIKSPD
PTKSNNAGMGIVHATYKPEYQVLNQWSIPLGNHTAQMAEIAAVEFACKKA
LKIPGPVLVITDSFYVAESANKELPYWKSNGFVNNKPLKHISKWKSIAEC
LSMKPDITIQHEKGHQPTNTSIHTEGNALADKLATQGSYVVN
3D structure
PDB7ksf Crystal Structure of a Retroviral Polyprotein: Prototype Foamy Virus Protease-Reverse Transcriptase (PR-RT).
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.26.4: ribonuclease H.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A D601 G602 E648 D592 G593 E639
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004190 aspartic-type endopeptidase activity
GO:0004523 RNA-DNA hybrid ribonuclease activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7ksf, PDBe:7ksf, PDBj:7ksf
PDBsum7ksf
PubMed34452360
UniProtA0A1Q1N9V8

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