Structure of PDB 7krt Chain A

Receptor sequence
>7krtA (length=599) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
GKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQDGCTLVG
QPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDA
WVEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQR
QATKDAGRIAGLEVKRIINEPTAAALAYGLDKGTGNRTIAVYDLGGGAFD
ISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDSRLINYLVEEFKKDQGID
LRNDPLAMQRLKEAAEKAKIELSSAQQTDVNLPYITADATGPKHMNIKVT
RAKLESLVEDLVNRSIEPLKVALQDAGLSVSDIDDVILVGGQTRMPMVQK
KVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLLDVTPLSLGI
ETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAADN
KSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITI
KASSGLNEDEIQKMVRDAEANAEADRKCEELVQTRNQGDHLLHSTRKQVE
EAGDKLPADDKTAIESALTALETALKGEDKAAIEAKMQELAQVSQKLME
3D structure
PDB7krt Conformational equilibria in allosteric control of Hsp70 chaperones.
ChainA
Resolution2.79 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A G10 T11 T12 N13 K70 G196 G197 K270 S274 G342 Q343 R345 G9 T10 T11 N12 K69 G195 G196 K269 S273 G341 Q342 R344
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0016887 ATP hydrolysis activity
GO:0016989 sigma factor antagonist activity
GO:0031072 heat shock protein binding
GO:0043531 ADP binding
GO:0044183 protein folding chaperone
GO:0051082 unfolded protein binding
GO:0051087 protein-folding chaperone binding
GO:0140662 ATP-dependent protein folding chaperone
Biological Process
GO:0006260 DNA replication
GO:0006457 protein folding
GO:0009408 response to heat
GO:0034620 cellular response to unfolded protein
GO:0042026 protein refolding
GO:0043335 protein unfolding
GO:0045892 negative regulation of DNA-templated transcription
GO:0051085 chaperone cofactor-dependent protein refolding
GO:0065003 protein-containing complex assembly
GO:1990169 stress response to copper ion
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016234 inclusion body
GO:0032991 protein-containing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7krt, PDBe:7krt, PDBj:7krt
PDBsum7krt
PubMed34453889
UniProtP0A6Y8|DNAK_ECOLI Chaperone protein DnaK (Gene Name=dnaK)

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