Structure of PDB 7kqm Chain A

Receptor sequence
>7kqmA (length=596) Species: 7070 (Tribolium castaneum) [Search protein sequence]
MVHYYRLSLKSRQKAPKIVNSKYNSILNIALKNFRLCKKHKTKKPVQILA
LLQEIIPKSYFGTTTNLKRFYKVVEKILTQSSFECIHLSVLHKCYDYDAI
PWLQNVEPNLRPKLLLKHNLFLLDNIVKPIIAFYYKPIKTLNGHEIKFIR
KEEYISFESKVFHKLKKMKYLVEVQDEVKPRGVLNIIPKQDNFRAIVSIF
PDSARKPFFKLLTSKIYKVLEEKYKTSGSLYTCWSEFTQKTQGQIYGIKV
DIRDAYGNVKIPVLCKLIQSIPTHLLDSEKKNFIVDHISNQFVAFRRKIY
KWNHGLLQGDPLSGCLCELYMAFMDRLYFSNLDKDAFIHRTVDDYFFCSP
HPHKVYDFELLIKGVYQVNPTKTRTNLPTHRHPQDEIPYCGKIFNLTTRQ
VRTLYKLPPNYEIRHKFKLWNFNNQISDDNPARFLQKAMDFPFICNSFTK
FEFNTVFNDQRTVFANFYDAMICVAYKFDAAMMALRTSFLVNDFGFIWLV
LSSTVRAYASRAFKKIVTYKGGKYRKVTFQCLKSIAWRAFLAVLKRRTEI
YKGLIDRIKSREKLTMKFHDGEVDASYFCKLPEKFRFVKINRKASI
3D structure
PDB7kqm Flexibility of telomerase in binding the RNA template and DNA telomeric repeat.
ChainA
Resolution2.73 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.49: RNA-directed DNA polymerase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna A K10 K139 L141 I187 I199 Y217 G309 P311 F441 C445 N446 K10 K139 L141 I187 I199 Y217 G309 P311 F441 C445 N446
BS02 dna A V342 D343 C390 G391 F417 K418 N421 N423 D440 P442 F443 N446 V342 D343 C390 G391 F417 K418 N421 N423 D440 P442 F443 N446
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003964 RNA-directed DNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006278 RNA-templated DNA biosynthetic process
GO:0071897 DNA biosynthetic process
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0005634 nucleus
GO:0005694 chromosome
GO:0043231 intracellular membrane-bounded organelle

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7kqm, PDBe:7kqm, PDBj:7kqm
PDBsum7kqm
PubMed34969861
UniProtQ0QHL8

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