Structure of PDB 7kop Chain A

Receptor sequence
>7kopA (length=185) Species: 11320 (Influenza A virus) [Search protein sequence]
SGLVPRGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAATCTH
LEVCFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLY
DYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKAD
YTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE
3D structure
PDB7kop Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential.
ChainA
Resolution2.33 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A H41 D108 E119 I120 H50 D98 E109 I110
BS02 MN A E80 D108 E70 D98
BS03 WTM A Y24 E26 K34 H41 E119 Y33 E35 K43 H50 E109
BS04 QQ4 A M12 G81 M21 G71
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:7kop, PDBe:7kop, PDBj:7kop
PDBsum7kop
PubMed
UniProtC6H0Y9

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