Structure of PDB 7kny Chain A

Receptor sequence
>7knyA (length=179) Species: 11320 (Influenza A virus) [Search protein sequence]
GSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAATCTHLEVCFM
YSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKENR
FIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLDEE
SRARIKTRLFTIRQEMASRSLWDSFRQSE
3D structure
PDB7kny Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential.
ChainA
Resolution2.48 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A H41 D108 E119 I120 H44 D92 E103 I104
BS02 MN A E80 D108 E64 D92
BS03 WTG A Y24 K34 A37 H41 D108 E119 Y27 K37 A40 H44 D92 E103
BS04 QQ4 A M12 F46 G81 M15 F49 G65
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:7kny, PDBe:7kny, PDBj:7kny
PDBsum7kny
PubMed
UniProtC6H0Y9

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