Structure of PDB 7klo Chain A

Receptor sequence
>7kloA (length=59) Species: 9606 (Homo sapiens) [Search protein sequence]
GSVNFVDLYVCMFCGRGNNEDKLLLCDGCDDSYHTFCLIPPLPDVPKGDW
RCPKCVAEE
3D structure
PDB7klo Recognition of Histone H3 Methylation States by the PHD1 Domain of Histone Demethylase KDM5A.
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 1.14.11.67: [histone H3]-trimethyl-L-lysine(4) demethylase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A C296 C299 H319 C322 C11 C14 H34 C37
BS02 ZN A C311 C314 C337 C340 C26 C29 C52 C55
External links
PDB RCSB:7klo, PDBe:7klo, PDBj:7klo
PDBsum7klo
PubMed33621062
UniProtP29375|KDM5A_HUMAN Lysine-specific demethylase 5A (Gene Name=KDM5A)

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