Structure of PDB 7kht Chain A

Receptor sequence
>7khtA (length=235) Species: 9606 (Homo sapiens) [Search protein sequence]
PNVPELILQLLQLEPDEDQVRARILGSLQEPTKSRPAAFGLLCRMADQTF
ISIVDWARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSI
LLVTGQEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKF
IILFSLDLKFLNNHILVKDAQEKANAALLDYTLCHYPHSGDKFQQLLLCL
VEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQA
3D structure
PDB7kht The acyl chains of phosphoinositide PIP3 alter the structure and function of nuclear receptor steroidogenic factor-1.
ChainA
Resolution2.504 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 WES A F262 Q339 A340 G341 L344 L347 Y436 K440 F39 Q116 A117 G118 L121 L124 Y213 K217
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity

View graph for
Molecular Function
External links
PDB RCSB:7kht, PDBe:7kht, PDBj:7kht
PDBsum7kht
PubMed33933440
UniProtQ13285|STF1_HUMAN Steroidogenic factor 1 (Gene Name=NR5A1)

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