Structure of PDB 7khm Chain A

Receptor sequence
>7khmA (length=290) Species: 9606 (Homo sapiens) [Search protein sequence]
WRCCQRVVGWVPVLFITFVVVWSYYAYVVELCVFTIFGNEENGKTVVYLV
AFHLFFVMFVWSYWMTIFTSPASPSKEFYLSNSEKERYEKEFSQERQQEI
LRRAARALPIYTTSASKTIRYCEKCQLIKPDRAHHCSACDSCILKMDHHS
PWVNNCVGFSNYKFFLLFLLYSLLYCLFVAATVLEYFIKFWTNELTDTRA
KFHVLFLFFVSAMFFISVLSLFSYHCWLVGKNRTTIESFRAPTFSYGPDG
NGFSLGCSKNWRQVFGDEKKYWLLPIFSSLGDGCSFPTRL
3D structure
PDB7khm Bivalent recognition of fatty acyl-CoA by a human integral membrane palmitoyltransferase.
ChainA
Resolution2.88 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.225: protein S-acyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C128 C131 H141 C122 C125 H135
BS02 ZN A C142 C145 H155 C162 C136 C139 H149 C156
BS03 PKZ A K135 H140 H141 C142 S143 H154 W158 C182 F220 I242 F245 K129 H134 H135 C136 S137 H148 W152 C176 F214 I236 F239
Gene Ontology
Molecular Function
GO:0016409 palmitoyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:7khm, PDBe:7khm, PDBj:7khm
PDBsum7khm
PubMed35140179
UniProtQ5W0Z9|ZDH20_HUMAN Palmitoyltransferase ZDHHC20 (Gene Name=ZDHHC20)

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