Structure of PDB 7kfa Chain A

Receptor sequence
>7kfaA (length=92) Species: 9606 (Homo sapiens) [Search protein sequence]
TATFHRCAKDPWRLPGTYVVVLKEETHLSQSERTARRLQAQAARRGYLTK
ILHVFHGLLPGFLVKMSGDLLELALKLPHVDYIEEDSSVFAQ
3D structure
PDB7kfa Identification of a PCSK9-LDLR disruptor peptide with in vivo function.
ChainA
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A W72 F150 A151 Q152 W12 F90 A91 Q92
External links
PDB RCSB:7kfa, PDBe:7kfa, PDBj:7kfa
PDBsum7kfa
PubMed34547225
UniProtQ8NBP7|PCSK9_HUMAN Proprotein convertase subtilisin/kexin type 9 (Gene Name=PCSK9)

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