Structure of PDB 7kdw Chain A

Receptor sequence
>7kdwA (length=113) Species: 9606 (Homo sapiens) [Search protein sequence]
TVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPM
DLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAEVLES
FFVQKLKGFKASR
3D structure
PDB7kdw New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development
ChainA
Resolution1.71 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 WCV A W2950 P2951 F2952 C3003 F3013 W28 P29 F30 C81 F91
Gene Ontology
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component
GO:0016589 NURF complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7kdw, PDBe:7kdw, PDBj:7kdw
PDBsum7kdw
PubMed32588860
UniProtQ12830|BPTF_HUMAN Nucleosome-remodeling factor subunit BPTF (Gene Name=BPTF)

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