Structure of PDB 7kd8 Chain A

Receptor sequence
>7kd8A (length=207) Species: 1196325 (Pseudomonas putida DOT-T1E) [Search protein sequence]
RTKEEAQETRAQIIEAAERAFYKRGVARTTLADIAELAGVTRGAIYWHFN
NKAELVQALLDSLHETHDHLARASESEDEVDPLGCMRKLLLQVFNELVLD
ARTRRINEILHHKCEFTDDMCEIRQQRQSAVLDIHKGWTLALANAVRRGQ
LPGELDAERAAVALYAYVDGLIRRWLLLPDSVDLLGDVEKWVDTGLDMLR
LSPALRK
3D structure
PDB7kd8 Epistasis shapes the fitness landscape of an allosteric specificity switch.
ChainA
Resolution1.71 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 STL A H70 D71 A74 R75 W141 H67 D68 A71 R72 W138
BS02 MG A T69 E99 T66 E96
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0001217 DNA-binding transcription repressor activity
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045892 negative regulation of DNA-templated transcription
Cellular Component
GO:0032993 protein-DNA complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7kd8, PDBe:7kd8, PDBj:7kd8
PDBsum7kd8
PubMed34548494
UniProtQ9AIU0|TTGR_PSEPT HTH-type transcriptional regulator TtgR (Gene Name=ttgR)

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