Structure of PDB 7kcx Chain A

Receptor sequence
>7kcxA (length=361) Species: 93062 (Staphylococcus aureus subsp. aureus COL) [Search protein sequence]
QATNSDVTPVQAANQYGYAGLSAAYEPTSAVNVSQTGQLLYQYNIDTKWN
PASMTKLMTMYLTLEAVNKGQLSLDDTVTMTNKEYIMSTLPELSNTKLYP
GQVWTIADLLQITVSNSSNAAALILAKKVSKNTSDFVDLMNNKAKAIGMK
NTHFVNPTGAENSRLRTFAPTKYKDQELTVTTARDYAILDLHVIKETPKI
LDFTKQLAPTTHAVTYYTFNFSLEGAKMSLPGTDGLKTGSSDTANYNHTI
TTKRGKFRINQVIMGAGDYKNLGGEKQRNMMGNALMERSFDQYKYVKILS
KGEQRINGKKYYVENDLYDVLPSDFSKKDYKLVVEDGKVHADYPREFINK
DYGPPTVEVHQ
3D structure
PDB7kcx PBP4-mediated beta-lactam resistance among clinical strains of Staphylococcus aureus.
ChainA
Resolution1.62 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1S7 A S75 S116 S139 R186 F241 T260 G261 S262 S263 Y291 S53 S94 S117 R164 F219 T238 G239 S240 S241 Y269
BS02 ZN A H362 D364 H340 D342
Gene Ontology
Molecular Function
GO:0008800 beta-lactamase activity
GO:0009002 serine-type D-Ala-D-Ala carboxypeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0030655 beta-lactam antibiotic catabolic process
GO:0046677 response to antibiotic

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7kcx, PDBe:7kcx, PDBj:7kcx
PDBsum7kcx
PubMed34151961
UniProtA0A0H2WY27

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