Structure of PDB 7kcq Chain A

Receptor sequence
>7kcqA (length=347) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
SIPETQKGVIFYESHGKLEYKDIPVPKPKANELLINVKYSGVCHTDLHAW
HGDWPLPTKLPLVGGHEGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMAC
EYCELGNESNCPHADLSGYTHDGSFQEYATADAVQAAHIPQGTDLAEVAP
VLCAGITVYKALKSANLMAGHWVAISGAAGGLGSLAVQYAKAMGYRVLGI
DGGEGKEELFRSIGGEVFIDFTKEKDIVGAVLKATDGGAHGVINVSVSEA
AIEASTRYVRANGTTVLVGMPAGAKCCSDVFNQVVKSISIVGSYVGNRAD
TREALDFFARGLVKSPIKVVGLSTLPEIYEKMEKGQIVGRYVVDTSK
3D structure
PDB7kcq Cryo-Electron Microscopy Structures of Yeast Alcohol Dehydrogenase.
ChainA
Resolution3.2 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) C43 T45 H48 H66 C153
Catalytic site (residue number reindexed from 1) C43 T45 H48 H66 C153
Enzyme Commision number 1.1.1.1: alcohol dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C43 H66 E67 C153 C43 H66 E67 C153
BS02 ZN A C97 C100 C103 C111 C97 C100 C103 C111
Gene Ontology
Molecular Function
GO:0004022 alcohol dehydrogenase (NAD+) activity
GO:0008270 zinc ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:7kcq, PDBe:7kcq, PDBj:7kcq
PDBsum7kcq
PubMed33620215
UniProtS5RZC2

[Back to BioLiP]