Structure of PDB 7kc7 Chain A

Receptor sequence
>7kc7A (length=451) Species: 940 (Hydrogenobacter thermophilus) [Search protein sequence]
MFKKVLVANRGEIACRVIRACKELGIQTVAIYNEIESTARHVKMADEAYM
IGVNPLDTYLNAERIVDLALEVGAEAIHPGYGFLAENEHFARLCEEKGIT
FIGPHWKVIELMGDKARSKEVMKRAGVPTVPGSDGILKDVEEAKRIAKEI
GYPVLLKASAGGGGRGIRISRNEEELVRNYENAYNEAVKAFGRGDLLLEK
YIENPKHIEFQVLGDKYGNVIHLGERDCSIQRRNQKLVEIAPSLLLTPEQ
REYYGSLVVKAAKEIGYYSAGTMEFIADEKGNLYFIEMNTRIQVEHPVTE
MITGVDIVKWQIRIAAGERLRYSQEDIRFNGYSIECRINAEDPKKGFAPS
IGTIERYYVPGGFGIRVEHASSKGYEITPYYDSLIAKLIVWAPLWEVAVD
RMRSALETYEISGVKTTIPLLINIMKDKDFRDGKFTTRYLEEHPHVFDYA
E
3D structure
PDB7kc7 Structure, Function, and Thermal Adaptation of the Biotin Carboxylase Domain Dimer from Hydrogenobacter thermophilus 2-Oxoglutarate Carboxylase.
ChainA
Resolution2.2 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) E274 E287 N289 E295 R337
Catalytic site (residue number reindexed from 1) E274 E287 N289 E295 R337
Enzyme Commision number 6.4.1.7: 2-oxoglutarate carboxylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A L155 K157 E199 Y201 I202 I276 L155 K157 E199 Y201 I202 I276
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0034029 2-oxoglutarate carboxylase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:7kc7, PDBe:7kc7, PDBj:7kc7
PDBsum7kc7
PubMed33464881
UniProtD3DJ42|2OCS_HYDTT 2-oxoglutarate carboxylase small subunit (Gene Name=cfiB)

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