Structure of PDB 7k87 Chain A

Receptor sequence
>7k87A (length=181) Species: 11320 (Influenza A virus) [Search protein sequence]
PRGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAATCTHLEVC
FMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYKE
NRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTLD
EESRARIKTRLFTIRQEMASRSLWDSFRQSE
3D structure
PDB7k87 Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential.
ChainA
Resolution2.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 QQ4 A M12 F46 I78 M17 F51 I64
BS02 MN A H41 D108 E119 I120 H46 D94 E105 I106
BS03 MN A E80 D108 E66 D94
BS04 W5V A K34 H41 D108 E119 K39 H46 D94 E105
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7k87, PDBe:7k87, PDBj:7k87
PDBsum7k87
PubMed36603507
UniProtC6H0Y9

[Back to BioLiP]