Structure of PDB 7k77 Chain A

Receptor sequence
>7k77A (length=182) Species: 11320 (Influenza A virus) [Search protein sequence]
VPRGSHMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAATCTHLEV
CFMYSDGGSKHRFEIIEGRDRIMAWTVVNSICNTTGVEKPKFLPDLYDYK
ENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTGEEMATKADYTL
DEESRARIKTRLFTIRQEMASRSLWDSFRQSE
3D structure
PDB7k77 Chemical scaffold recycling: Structure-guided conversion of an HIV integrase inhibitor into a potent influenza virus RNA-dependent RNA polymerase inhibitor designed to minimize resistance potential.
ChainA
Resolution2.78 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A H41 D108 E119 I120 H47 D95 E106 I107
BS02 MN A E80 D108 E67 D95
BS03 U3A A Y24 E26 K34 A37 H41 D108 E119 Y30 E32 K40 A43 H47 D95 E106
Gene Ontology
Biological Process
GO:0039694 viral RNA genome replication

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Molecular Function
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Biological Process
External links
PDB RCSB:7k77, PDBe:7k77, PDBj:7k77
PDBsum7k77
PubMed
UniProtC6H0Y9

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