Structure of PDB 7k6r Chain A

Receptor sequence
>7k6rA (length=122) Species: 9606 (Homo sapiens) [Search protein sequence]
MSTEDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYY
GVIKEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQ
CAEVLESFFVQKLKGFKASRSH
3D structure
PDB7k6r New inhibitors for the BPTF bromodomain enabled by structural biology and biophysical assay development.
ChainA
Resolution1.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 9ST A W2950 P2951 F2952 V2956 D2960 Y3006 N3007 F3013 W35 P36 F37 V41 D45 Y91 N92 F98
Gene Ontology
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component
GO:0016589 NURF complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7k6r, PDBe:7k6r, PDBj:7k6r
PDBsum7k6r
PubMed32588860
UniProtQ12830|BPTF_HUMAN Nucleosome-remodeling factor subunit BPTF (Gene Name=BPTF)

[Back to BioLiP]