Structure of PDB 7k15 Chain A

Receptor sequence
>7k15A (length=455) Species: 882,9606 [Search protein sequence]
GVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNLAL
ADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVWLITAMS
LDRYLAVARPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWK
TNMSLCFPRYPSEGHRAFHLIFEAVTGFLLPFLIVVASYSDIGRRLQARR
AKALIVYGSTTGNTEYTAETIARELADAGYEVDSRDAASVEAGGLFEGFD
LVLLGCSTWGDDSIELQDDFIPLFDSLEETGAQGRKVACFGCGDSSWEYF
CGAVDAIEEKLKNLGAEIVQDGLRIDGDPRAARDDIVGWAHDVRGAIRRF
RRSRRTGRLVVLIILTFAAFWLPYHVVNLAEAGRALAGQAAGLGLVGKRL
SLARNVLIALAFLSSSVNPVLYAFAGGGLLRSAGVGFVAKLLEGTGAEFL
EVLFQ
3D structure
PDB7k15 Structural insights on ligand recognition at the human leukotriene B4 receptor 1.
ChainA
Resolution2.88 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VRJ A F74 L78 H94 C97 R156 C168 P170 W234 Y237 N268 I271 A274 F275 F62 L66 H82 C85 R144 C156 P158 W371 Y374 N405 I408 A411 F412
BS02 FMN A S1010 T1011 T1012 N1014 T1015 S1058 T1059 W1060 G1061 W1098 Y1100 S209 T210 T211 N213 T214 S257 T258 W259 G260 W297 Y299
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0004974 leukotriene receptor activity
GO:0009055 electron transfer activity
GO:0010181 FMN binding
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:7k15, PDBe:7k15, PDBj:7k15
PDBsum7k15
PubMed34016973
UniProtP00323|FLAV_NITV2 Flavodoxin (Gene Name=DVU_2680);
Q15722|LT4R1_HUMAN Leukotriene B4 receptor 1 (Gene Name=LTB4R)

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