Structure of PDB 7k0a Chain A

Receptor sequence
>7k0aA (length=196) Species: 132473 (Streptomyces alboniger) [Search protein sequence]
KPTVRLATRDDVPRAVRTLAAAFADYPATRHTVDPDRHIERVTELQELFL
TRVGLDIGKVWVADDGAAVAVWTTPESVEAGAVFAEIGPRMAELSGSRLA
AQQQMEGLLAPHRPKEPAWFLATVGVSPDHQGKGLGSAVVLPGVEAAERA
GVPAFLETSAPRNLPFYERLGFTVTADVEVPEGPRTWCMTRKPGAS
3D structure
PDB7k0a Structure-guided selection of puromycin N-acetyltransferase mutants with enhanced selection stringency for deriving mammalian cell lines expressing recombinant proteins.
ChainA
Resolution2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VQ1 A F27 F53 T77 F124 A126 T127 V128 E161 F23 F49 T73 F120 A122 T123 V124 E157
BS02 COA A A26 Y30 V128 G129 V130 Q135 G136 G138 G140 S141 T162 N167 F170 R173 A22 Y26 V124 G125 V126 Q131 G132 G134 G136 S137 T158 N163 F166 R169
Gene Ontology
Molecular Function
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
Biological Process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:7k0a, PDBe:7k0a, PDBj:7k0a
PDBsum7k0a
PubMed33664348
UniProtP13249|PUAC_STRAD Puromycin N-acetyltransferase (Gene Name=pac)

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