Structure of PDB 7jyd Chain A

Receptor sequence
>7jydA (length=240) Species: 9606 (Homo sapiens) [Search protein sequence]
ASIPHLILELLKCEPDEPQVQAKIMAYLQQEQANRSKHEKLSTFGLMCKM
ADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVVHG
KEGSIFLVTGQQVDYSIIASQAGATLNNLMSHAQELVAKLRSLQFDQREF
VCLKFLVLFSLDVKNLENFQLVEGVQEQVNAALLDYTMCNYPQQTEKFGQ
LLLRLPEIRAISMQAEEYLYYKHLNGDVPYNNLLIEMLHA
3D structure
PDB7jyd Tapping into a phospholipid-LRH-1 axis yields a powerful anti-inflammatory agent with in vivo activity against colitis
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A F354 R361 M375 Q379 E534 F56 R63 M77 Q81 E236
BS02 VQA A F342 M345 C346 A349 H390 A420 L424 Y516 K520 F44 M47 C48 A51 H92 A122 L126 Y218 K222
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity

View graph for
Molecular Function
External links
PDB RCSB:7jyd, PDBe:7jyd, PDBj:7jyd
PDBsum7jyd
PubMed
UniProtO00482|NR5A2_HUMAN Nuclear receptor subfamily 5 group A member 2 (Gene Name=NR5A2)

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