Structure of PDB 7jwi Chain A

Receptor sequence
>7jwiA (length=277) Species: 10090 (Mus musculus) [Search protein sequence]
GPHSMRYFETAVSRPGLEEPRYISVGYVDNKEFVRFDSDAENPRYEPRAP
WMEQEGPEYWERETQKAKGQEQWFRVSLRNLLGYYNQSAGGSHTLQQMSG
CDLGSDWRLLRGYLQFAYEGRDYIALNEDLKTWTAADMAAQITRRKWEQS
GAAEHYKAYLEGECVEWLHRYLKNGNATLLRTDSPKAHVTHHPRSKGEVT
LRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVP
LGKEQNYTCRVYHEGLPEPLTLRWEPP
3D structure
PDB7jwi Canonical T cell receptor docking on peptide-MHC is essential for T cell signaling.
ChainA
Resolution3.02 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y7 E63 K66 Q70 W73 S77 N80 Y84 L95 Q97 Y123 T143 K146 W147 S150 H155 Y156 Y159 W167 Y171 Y7 E63 K66 Q70 W73 S77 N80 Y84 L95 Q97 Y123 T143 K146 W147 S150 H155 Y156 Y159 W167 Y171
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation

View graph for
Biological Process
External links
PDB RCSB:7jwi, PDBe:7jwi, PDBj:7jwi
PDBsum7jwi
PubMed34083463
UniProtP01899|HA11_MOUSE H-2 class I histocompatibility antigen, D-B alpha chain (Gene Name=H2-D1)

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