Structure of PDB 7jtv Chain A

Receptor sequence
>7jtvA (length=884) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
MATQEEILDAALVSGDSSQLTDSHLVALRLQQQVERIRQTRTQLLDGLYQ
NLSQAYDPGAASMWVLPANPDNTLPFLIGDKGRVLASLSLEAGGRGLAYG
TNVLTQLSGTNAAHAPLLKRAVQWLVNGDPGAATAKDFKVSVVGVDKTAA
LNGLKSAGLQPADAACNALTDASCASTSKLLVLGNGASAASLSATVRARL
QAGLPILFVHTNGWNQSSTGQQILAGLGLQEGPYGGNYWDKDRVPSSRTR
TRSVELGGAYGQDPALVQQIVDGSWRTDYDWSKCTSYVGRTTCDDVPGLS
DFSKRVDVLKGALDAYNQKAQNLFALPGTTSLRLWLLWADAVRQNIRYPM
DKAADTARFQETFVADAIVGYVREAGAAQKELGSYAGQRQQSMPVSGSEE
TLTLTLPSAQGFTAIGRMAAPGKRLSIRIEDAGQASLAVGLNTQRIGSTR
LWNTRQYDRPRFLKSPDIKLQANQSVALVSPYGGLLQLVYSGATPGQTVT
VKVTGAASQPFLDIQPGEDSSQAIADFIQALDADKADWLEIRSGSVEVHA
KVEKVRGSIDKDYGGDVQRFIRELNEVFIDDAYTLAGFAIPNQAKTPAIQ
QECAARGWDCDSETLHKLPGTQHINVDQYAQCGGGCSGNPYDQTWGLNPR
GWGESHQLGHNLQVNRLKVYGGRSGEISNQIFPLHKDWRVLREFGQNLDD
TRVNYRNAYNLIVAGRAEADPLAGVYKRLWEDPGTYALNGERMAFYTQWV
HYWADLKNDPLQGWDIWTLLYLHQRQVDKSDWDANKAALGYGTYAQRPGN
SGDASSTDGNDNLLLGLSWLTQRDQRPTFALWGIRTSAAAQAQVAAYGFA
EQPAFFYANNRTNEYSTVKLLDMSQGSPAWPFPL
3D structure
PDB7jtv Structural evidence for a proline-specific glycopeptide recognition domain in an O-glycopeptidase.
ChainA
Resolution2.45 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A W254 Y274 Y278 W279 W214 Y234 Y238 W239
BS02 ZN A H696 H700 E716 H656 H660 E676
Gene Ontology
Molecular Function
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0015628 protein secretion by the type II secretion system
GO:0030163 protein catabolic process
GO:0043952 protein transport by the Sec complex
GO:1903237 negative regulation of leukocyte tethering or rolling
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7jtv, PDBe:7jtv, PDBj:7jtv
PDBsum7jtv
PubMed33030205
UniProtQ9I5W4|IMPA_PSEAE Immunomodulating metalloprotease (Gene Name=impA)

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