Structure of PDB 7jpr Chain A

Receptor sequence
>7jprA (length=352) Species: 9606 (Homo sapiens) [Search protein sequence]
SVLEEARLRLHVSAVPESLPCREQEFQDIYNFVESKLLDHTGGCMYISGV
PGTGKTATVHEVIRCLQQAAQANDVPPFQYIEVNGMKLTEPHQVYVQILQ
KLTGQKATANHAAELLAKQFTTVLLVDELDLLWTHKQDIMYNLFDWPTHK
EARLVVLAIANTMDLPERIMLTRMCFQPYTYSQLQQILRSRLKHLKAFED
DAIQLVARKVAALSGDARRCLDICRRATEICEFSQGLVTIAHSMEAVDEM
FSSSYITAIKNSSVLEQSFLRAILAEFRRSGLEEATFQQIYSQHVALCRM
EGLPYPTMSETMAVCSHLGSCRLLLVEPSRNDLLLRVRLNVSQDDVLYAL
KD
3D structure
PDB7jpr The dynamic nature of the human Origin Recognition Complex revealed through five cryoEM structures.
ChainA
Resolution4.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A V500 L504 P536 G539 K540 T541 Y681 I689 R693 A719 R720 V15 L19 P51 G54 K55 T56 Y179 I187 R191 A217 R218
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity

View graph for
Molecular Function
External links
PDB RCSB:7jpr, PDBe:7jpr, PDBj:7jpr
PDBsum7jpr
PubMed32808929
UniProtQ13415|ORC1_HUMAN Origin recognition complex subunit 1 (Gene Name=ORC1)

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