Structure of PDB 7jo9 Chain A

Receptor sequence
>7jo9A (length=98) Species: 9606 (Homo sapiens) [Search protein sequence]
KPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQS
SAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
3D structure
PDB7jo9 Structural basis of nucleosome-dependent cGAS inhibition.
ChainA
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R42 R72 R6 R36
BS02 dna A Y41 V46 R49 K64 R69 Y5 V10 R13 K28 R33
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
Cellular Component
GO:0000786 nucleosome
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0070062 extracellular exosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:7jo9, PDBe:7jo9, PDBj:7jo9
PDBsum7jo9
PubMed32913000
UniProtQ71DI3|H32_HUMAN Histone H3.2 (Gene Name=H3C15)

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