Structure of PDB 7jlv Chain A

Receptor sequence
>7jlvA (length=437) Species: 4100 (Nicotiana benthamiana) [Search protein sequence]
DLVGIESQIKKLSSLLRMDLKGVRLVGIWGMGGVGKTTAARALFNRYYQN
FESACFLEDVKEYLQHHTLLYLQKTLLSKLLKVEFVDCTDTEEMCVILKR
RLCSKKVLVVLDDVNHNDQLDKLVGAEDWFGSGSRIVITTRDMKLLKNHD
VHETYEIKVLEKDEAIELFNLHAFKRSSPEKEFKELLNLVVDYTGGLPLA
LKVLGSLLYKEDLDVWISTIDRLKDNPEGEIMATLKISFDGLRDYEKSIF
LDIACFFRGYNQRDMTALFHASGFHPVLGVKTLVEKSLIFILEDKIQMHD
LMQEMGRQIAVQESPMRRIYRPEDVKDACIGDMRKEAIEGLLLTEPEQFE
EGELEYMYSAEALKKTRRLRILVKEYYNRGFDEPVAYLPNSLLWLEWRNY
SSNSFPSNFEPSKLVYLTMKGSSIIELWNGAKRLAFL
3D structure
PDB7jlv Structure of the activated ROQ1 resistosome directly recognizing the pathogen effector XopQ.
ChainA
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.2.-
3.2.2.6: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A L190 V191 G220 G221 V222 K224 T225 P386 L2 V3 G32 G33 V34 K36 T37 P198
Gene Ontology
Molecular Function
GO:0003953 NAD+ nucleosidase activity
GO:0005515 protein binding
GO:0016787 hydrolase activity
GO:0043531 ADP binding
GO:0061809 NAD+ nucleotidase, cyclic ADP-ribose generating
Biological Process
GO:0006950 response to stress
GO:0006952 defense response
GO:0007165 signal transduction

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Molecular Function
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Biological Process
External links
PDB RCSB:7jlv, PDBe:7jlv, PDBj:7jlv
PDBsum7jlv
PubMed33273074
UniProtA0A290U7C4|ROQ1_NICBE Disease resistance protein Roq1 (Gene Name=ROQ1)

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