Structure of PDB 7jlj Chain A

Receptor sequence
>7jljA (length=236) Species: 1423 (Bacillus subtilis) [Search protein sequence]
RYTKEDILKGEIPEHIAIIMDGNGRWAKKRSLPRIAGHHEGMKVVKRTTK
LANELGVKVLTLYAFKRPKMEVDFLMKLPEEFLNTYLPELVEENVQVRII
GDETALPAHTLRAIEKAVQDTAQNDGMILNFALNYGGRTEIVSAAKSLAE
KVKEGSLNIEDIDESLFSTYLMTESLQDPELLIRTSGEIRLSNFMLWQVA
YSEFVFTDVLWPDFKEDHFLQALGEFQQRGRRFGGI
3D structure
PDB7jlj Structural Insights into the Inhibition of Undecaprenyl Pyrophosphate Synthase from Gram-Positive Bacteria.
ChainA
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.5.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 53Q A M39 N42 V64 F84 L99 M100 P103 F155 L157 N158 M20 N23 V45 F65 L75 M76 P79 F131 L133 N134
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004659 prenyltransferase activity
GO:0008834 di-trans,poly-cis-undecaprenyl-diphosphate synthase activity
GO:0016740 transferase activity
GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups
GO:0030145 manganese ion binding
GO:0045547 dehydrodolichyl diphosphate synthase activity
GO:0046872 metal ion binding
Biological Process
GO:0016094 polyprenol biosynthetic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:7jlj, PDBe:7jlj, PDBj:7jlj
PDBsum7jlj
PubMed34473495
UniProtO31751|ISPT_BACSU Isoprenyl transferase (Gene Name=uppS)

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