Structure of PDB 7jl7 Chain A

Receptor sequence
>7jl7A (length=141) Species: 7955 (Danio rerio) [Search protein sequence]
FRYSLNYPNIGHCIIINNKNFDRRTGMNPRNGTDVDAGNVMNVFRKLGYI
VKVYNDQTVAQIMQVLTTVAHDDHSRCASLVCVLLSHGDEGVFFGTDTSV
DLKSLTSLFRGDRCPSLVGKPKLFFIQACRGTELDPGVETD
3D structure
PDB7jl7 Remodeling hydrogen bond interactions results in relaxed specificity of Caspase-3.
ChainA
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.56: caspase-3.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A R67 H124 Q164 C166 R30 H87 Q127 C129
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7jl7, PDBe:7jl7, PDBj:7jl7
PDBsum7jl7
PubMed33448281
UniProtA0A2R8QUC0

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