Structure of PDB 7jkx Chain A

Receptor sequence
>7jkxA (length=127) Species: 9606 (Homo sapiens) [Search protein sequence]
LENPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPTEE
3D structure
PDB7jkx Bromodomain-containing protein 4 (BRD4) bromodomain 1 (BD1) complexed with YF3-6
ChainA
Resolution1.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 Y36 A W81 P82 F83 Q85 V87 D88 K91 L92 Y139 N140 I146 M149 W40 P41 F42 Q44 V46 D47 K50 L51 Y98 N99 I105 M108
External links
PDB RCSB:7jkx, PDBe:7jkx, PDBj:7jkx
PDBsum7jkx
PubMed
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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