Structure of PDB 7jih Chain A

Receptor sequence
>7jihA (length=159) Species: 9606 (Homo sapiens) [Search protein sequence]
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDDSYRKQVVIDGETCLLDILD
TEGQEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSD
DVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFY
TLVREIRQH
3D structure
PDB7jih Regulation of GTPase function by autophosphorylation.
ChainA
Resolution1.989 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 GNP A G13 G15 K16 S17 A18 F28 D30 N116 K117 D119 G13 G15 K16 S17 A18 F28 D30 N109 K110 D112
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7jih, PDBe:7jih, PDBj:7jih
PDBsum7jih
PubMed35202574
UniProtP01112|RASH_HUMAN GTPase HRas (Gene Name=HRAS)

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