Structure of PDB 7jhn Chain A

Receptor sequence
>7jhnA (length=327) Species: 9606 (Homo sapiens) [Search protein sequence]
PEAYWNREQEKLNRQYNPILSISHLNYCEPDLRVTSVVTGFNNLPDRFKD
FLLYLRCRNYSLLIDQPDKCAKKPFLLLAIKSLTPHFARRQAIRESWGQE
SNAQTVVRVFLLGQTPPEDNHPDLSDMLKFESEKHQDILMWNYRDTFFNL
SLKEVLFLRWVSTSCPDTEFVFKGDDDVFVNTHHILNYLNSLSKTKAKDL
FIGDVIHNAGPHRDKKLKYYIPEVVYSGLYPPYAGGGGFLYSGHLALRLY
HITDQVHLYPIDDVYTGMCLQKLGLVPEKHKGFRTFDIEEKNKNNICSYV
DLMLVHSRKPQEMIDIWSQLQSAHLKC
3D structure
PDB7jhn Structures and mechanism of human glycosyltransferase beta 1,3-N-acetylglucosaminyltransferase 2 (B3GNT2), an important player in immune homeostasis.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.149: N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GAL A H282 Y289 Y303 D333 H212 Y219 Y233 D263
BS02 MG A D247 H376 D177 H306
BS03 UDP A S150 L151 D215 T216 L220 K223 D245 D246 K288 Y289 S82 L83 D145 T146 L150 K153 D175 D176 K218 Y219
Gene Ontology
Molecular Function
GO:0016758 hexosyltransferase activity
Biological Process
GO:0006486 protein glycosylation
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7jhn, PDBe:7jhn, PDBj:7jhn
PDBsum7jhn
PubMed33158990
UniProtQ9NY97|B3GN2_HUMAN N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 (Gene Name=B3GNT2)

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